Gastrointestinal regulation of food intake

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Gastrointestinal regulation of food intake.

Despite substantial fluctuations in daily food intake, animals maintain a remarkably stable body weight, because overall caloric ingestion and expenditure are exquisitely matched over long periods of time, through the process of energy homeostasis. The brain receives hormonal, neural, and metabolic signals pertaining to body-energy status and, in response to these inputs, coordinates adaptive a...

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Role of peptides from gastrointestinal cells in food intake regulation.

Many peptides are contained in specific cells distributed throughout the gastrointestinal tract. Some are known to be released by the presence of specific components of food and to affect specific gastrointestinal functions related to digestion and absorption of nutrients. For many of the more recently identified peptides, however, stimuli for release and physiological functions are unknown. Im...

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Nervous regulation of food intake.

Q LORIC BALANCE depends upon the regulation of biologic energy exchange. Four important variables are concerned in energy balance : ( 1) food intake, (2) energy storage, (3) energy utilization through activity or work and (4) loss of energy in the production of heat. The caloric balance would thus be regulated by the various mechanisms which regulate the caloric intake in the form of food intak...

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Hormonal regulation of food intake.

Our knowledge of the physiological systems controlling energy homeostasis has increased dramatically over the last decade. The roles of peripheral signals from adipose tissue, pancreas, and the gastrointestinal tract reflecting short- and long-term nutritional status are now being described. Such signals influence central circuits in the hypothalamus, brain stem, and limbic system to modulate n...

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Food intake, feelings, and gastrointestinal physiology.

THE CLASSICAL METHODS for studying the inhibitory controls of food intake involve the manipulation of tissues hypothesized to signal sites in the brain which in turn remove or reduce excitatory influences on the muscles involved in eating (4). It is not yet possible to study all the links in this chain, from the stimuli in the periphery through to the central nervous system and back down to the...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 2007

ISSN: 0021-9738

DOI: 10.1172/jci30227